Development of an electrochemical biosensor for Vitamin B12 using D-phenylalanine nanotubes
Paper ID : 1479-UFGNSM-FULL
Authors:
Maryam Moazeni Afarani *1, Fathallah Karimzadeh2, Ahmad Kermanpur3, Alireza allafchian4
1No. D51, Negin-e-Moshtagh complex,Jei-shir St., Isfahan 8158166155, Iran
2Department Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111, Iran
3Department of Materials Engineering, Isfahan University of Technology, Isfahan, 84156-83111, Iran
4Research Institute for Nanotechnology and Advanced Materials, Isfahan University of Technology
Abstract:
. In the past decades, biosensors are one of the most interesting topics among researchers and scientist. The biosensors are used in several applications such as determining food quality, control and diagnose clinical problems and metabolic control. Therefore, many efforts have been carried out to design and develop a new generation of these systems. On the other hand nanotechnology by improving the performance of sensors has created an excellent outlook. Using nanomaterials such as nanoparticles, nanotubes, nanowires, and nanorods in diagnostic tools has been significantly increased accuracy, sensitivity and improved detection limits in sensors. In this study, the one-dimensional morphology of the D-phenylalanine was assembled on the surface of the gold electrode. In the next step electrochemical performance of the modified electrode was investigated by Cyclic Voltammetry (CV), Electrochemical Impedance Spectroscopy (EIS) and Differential Pals Voltammograms (DPV). Finally, by measuring the different concentrations of vitamin B12, the detection limit of the biosensor was obtained 1.6 μM.
Keywords:
Self-assembly, Phenylalanine, Electrochemical Biosensor, Nanowire
Status : Paper Accepted (Poster Presentation)