| Sol-gel synthesis of (Ca-Ba)TiO3 nanoparticles for bone tissue engineering |
| Paper ID : 1066-UFGNSM-FULL |
| Authors: |
|
Narges Ahmadi khoie *1, Mahshid Kharaziha2, sheyda labbaf3 18415683111 2department of materials science, Isfahan university of technology 3department of materials science,Isfahan university of technology |
| Abstract: |
| Piezoelectric materials are the group of smart materials which their electrical and electromechanical properties can be useful in biomedical applications like bone tissue engineering. The advantage of these materials is that they can provide electrical signals with no external source power. Besides bone is piezoelectric natural material in which electrical pulses are effective agents for bone remodeling. In order to consider the effect of piezoelectric materials in bone healing, wide researches have focused on the piezoelectric powders and scaffolds. Between various types of materials, BaTiO3 and CaTiO3 are nontoxic piezoelectic ceramics which can be helpful in bone regeneration and remodeling. Therefore the combination of these two ceramics could provide suitable piezoelectricity, bioactivity and biocompatibility for bone tissue engineering applications. The aim of this research is to synthesize (Cax-Ba1-x)TiO3 (x=0, 0.1, 0.2, 0.4, 1) nanopowder using sol-gel method. In this regard, calcium acetate, barium acetate and titanium-tetra-isopropoxide were used as precursors. After preparation of (Cax-Ba1-x)TiO3 with various ratio of Ca/Ba, calcination was performed at various temperatures 900-1100 °C for 1 hour. Finally, the formation of (Ca-Ba)TiO3 nanoparticles was confirmed by X-ray diffraction, scanning electron microscopy and dynamic light scattering. Additionally, the bioactivity of (Cax-Ba1-x)TiO3 powders was evaluated using the soaking in simulated body fluid (SBF) solution. Results confirmed that pure (Cax-Ba1-x)TiO3 was synthesized for the first time without secondary phases. Moreover, compared to pure CaTiO3 and BaTiO3, the particle size and crystallite size of (Cax-Ba1-x)TiO3 (x=0, 0.1, 0.2, 0.4, 1) powder significantly reduced depending on the Ca/Ba ratio. Moreover, compared to pure BaTiO3 and CaTiO3, the bioactivity of (Cax-Ba1-x)TiO3 (x=0, 0.1, 0.2, 0.4, 1) improved which might be due to the formation of defects during the substitution of elements in the structure. Our result confirmed that (Cax-Ba1-x)TiO3 nanopowder could be a promising bioactive ceramic for bone tissue engineering application. |
| Keywords: |
| sol-gel,piezoelectric,bone tissue engneering,barium calcium titanate |
| Status : Paper Accepted (Poster Presentation) |
